megatomi.com - An Overview

Our new Apparent+ tissue clearing method is the only method that delipidates samples without having transform in morphology and with nominal impact on structural integrity.

Megatome is actually a vibrating microtome made to section a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome enables significant-throughput tissue sectioning with uniform surface area profile, in addition to nominal tissue harm and knowledge loss.

Antibodies might acquire weeks to diffuse by only a few millimeters of tissue, with a steep labeling gradient from floor to Main.

Megatome is suitable for precision: the blade vibrates at an increased frequency and larger amplitude vary than other microtomes, and incorporates a one of a kind deflection Handle system.

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Megatome is a novel microtome that permits for high-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – megatomi.com with minimal tissue damage and knowledge reduction.

It’s time for you to upgrade your microtome to Megatome. With accurate high-frequency slicing for an unmatched number of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous apps.

Fully delipidate entire mouse brains or comparably sized samples in just one day with SmartBatch+, or in a single week with our passive clearing package.

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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for many rounds of processing.

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Our novel SHIELD tissue preservation approach types intramolecular bonds employing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.